Article ID Journal Published Year Pages File Type
7635154 Journal of Proteomics 2016 45 Pages PDF
Abstract
Understanding the mechanism of extracellular vesicles such as exosomes in breast cancer progression and identification of molecular biomarker candidates for breast cancer are of great significance. Exosomes, which function as informative vesicles, can help to understand disease mechanisms and are ideal candidates for identification of diagnostic biomarker for various diseases. Here, we identified the molecular mechanism of action of EDIL3 on extracellular vesicles in breast cancer and its role in vivo, and a biomarker candidate for metastatic breast cancer. Furthermore, it is suggested that EDIL3 might be employed as a therapeutic target that limits disease progression.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
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