| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7638321 | Journal of Proteomics | 2012 | 18 Pages |
Abstract
⺠Response to iron was assayed in mouse bone marrow macrophages through high-res 2-DE. ⺠Iron induced metabolic dysregulation at the transcript, protein and metabolic level. ⺠GAPDH relocated to the membrane and was probably involved in iron homeostasis. ⺠Over-activation of Krebs cycle was paralleled by oxidative stress. ⺠The integration of omics approaches supported and expanded proteomics results.
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Authors
Rita Polati, Annalisa Castagna, Alessandra Maria Bossi, Tiziana Alberio, Ivana De Domenico, Jerry Kaplan, Anna Maria Timperio, Lello Zolla, Federica Gevi, Angelo D'Alessandro, Ryan Brunch, Oliviero Olivieri, Domenico Girelli,