| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7638322 | Journal of Proteomics | 2012 | 8 Pages |
Abstract
⺠Hepcidin, a 25 amino acid hormone, is the key regulator of iron metabolism. ⺠We measured, for the first time, serum hepcidin-20 at population level by SELDI-TOF-MS. ⺠Detectable amount of hepcidin 20 were found in more than half of 1577 individuals. ⺠The Hep25:hep20 ratio was not constant but increased with increasing iron stores. ⺠Our results point toward a possible active regulation of hepcidin-20 production.
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Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Natascia Campostrini, Michela Traglia, Nicola Martinelli, Michela Corbella, Massimiliano Cocca, Daniele Manna, Annalisa Castagna, Corrado Masciullo, Laura Silvestri, Oliviero Olivieri, Daniela Toniolo, Clara Camaschella, Domenico Girelli,