Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7638371 | Journal of Proteomics | 2012 | 12 Pages |
Abstract
⺠We studied proteome changes associated with aristolochic acids (AA) exposure in mice. ⺠Early proteome alterations were examined in mice urine, plasma and kidney tissue. ⺠Several proteins were differentially expressed in both AA exposed and control mice. ⺠These proteins are consistent with renal pathogenesis of endotoxicity and cancer. ⺠Several proteins were identified as possible biomarker candidates for AA nephropathy.
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Authors
Marijana Rucevic, Thomas Rosenquist, Lucas Breen, Lulu Cao, James Clifton, Douglas Hixson, Djuro Josic,