Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7638424 | Journal of Proteomics | 2012 | 13 Pages |
Abstract
⺠HPLC-Q-TOF-based untargeted metabolomics was performed on stored RBC concentrates. ⺠We observed a rapid fall of glycolytic rate and accumulation of end products. ⺠Metabolism shifted towards the oxidative phase of pentose phosphate pathway. ⺠Oxidative stress was exacerbated in RBCs and supernatants. ⺠Metabolism proceeded from PPP towards purine salvage pathway.
Related Topics
Physical Sciences and Engineering
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Authors
Federica Gevi, Angelo D'Alessandro, Sara Rinalducci, Lello Zolla,