| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7638466 | Journal of Proteomics | 2012 | 19 Pages |
Abstract
⺠Storage quality measures were evaluated in leukoreduced (L) and non-L (N) RBCs. ⺠Length of storage enhances RBCs lesions but leukoreduction alleviates them. ⺠The L-effect is expressed either for a part or for the whole of the storage period. ⺠The residual leukocytes trigger senescence and removal signaling in stored RBCs. ⺠A mechanistic basis for the improved storage/transfusions of L-units is provided.
Keywords
CSLMRBCsMCHCPrx2PCIMCVMCHBS3dichlorofluoresceinSAGMRDWHCTN-ethylmaleimideDcfRed blood cellscpdt-BHPcalcium accumulationOxidative stresscitrate-phosphate-dextroseStorage lesionRed cell distribution widthPhosphatidylserinemean cell volumeconfocal laser scanning microscopyNEMhematocritHemoglobintert-butyl hydroperoxidePeroxiredoxin 2Membrane proteome
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Marianna H. Antonelou, Vassilis L. Tzounakas, Athanassios D. Velentzas, Konstantinos E. Stamoulis, Anastasios G. Kriebardis, Issidora S. Papassideri,