Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7642868 | Microchemical Journal | 2014 | 8 Pages |
Abstract
The use of anionic surfactants and the application of a deconvolution procedure were investigated as suitable methods to provide electrochemical peak separation in the simultaneous detection of the fluoroquinolones levofloxacin (LEVO) and norfloxacin (NOR). Concurrently, an electroanalytical methodology was developed based on the simultaneous determination of both fluoroquinolones using a mathematical treatment via baseline correction. We also developed a deconvolution procedure to separate overlapping peaks. These methods provided satisfactory peak separation and intensification of peak current, allowing efficient quantification of analytes in both tablets and biological samples with recovery values ranging from 88.1%-107.5%.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Uendinara Bilibio, Luiz Henrique de Oliveira, Valdir Souza Ferreira, Magno Aparecido Gonçalves Trindade,