Curtain flow chromatography ('the infinite diameter column') with automated injection and high sample through-put: The results of an inter-laboratory study

The outcome from the study was that calibration curves derived from analyses undertaken on curtain flow columns were linear. The limits of quantification and detection were almost three times lower when curtain flow columns were used than when standard columns where used. The best results were obtained when the HPLC system was designed such that it could deliver a synchronised solvent flow through both the peripheral and central column entry ports.