| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7645319 | Revue Francophone des Laboratoires | 2017 | 9 Pages |
Abstract
From now on, idiopathic membranous nephropathy could be ascertained as autoimmune disease, since autoantibodies were isolated against glomerular components, or even against usual dietary antigens. Some of them, like anti-PLA2R antibodies or anti-THSD7A are useful to monitor the disease activity and to follow the treatment efficacy. Genetic polymorphisms of PLA2R gene may be the underlying cause of idiopathic membranous nephropathy. This translational research opens a new field to develop innovative targeted therapies.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Charline Miot, Caroline Poli, Céline Beauvillain, Pascale Jeannin, Gilles Renier, Jean-François Subra, Alain Chevailler,