| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7652875 | Revue Francophone des Laboratoires | 2013 | 10 Pages |
Abstract
Most hepatocellular carcinomas (HCC) arise in a background of chronic liver diseases leading to cirrhosis via the development of preneoplastic nodules. According to the last international recommendations, biopsy for HCC diagnosis is restricted to liver nodules > 1Â cm with atypical features on imaging. High grade dysplastic nodule is the main differential diagnostic of HCC, and the use of immunohistochemistry with specific markers has shown a significant added-value. HCC prognosis may also be evaluated on biopsy, mainly via the evaluation of tumor differentiation. Lastly, risks of biopsy are really limited, with a low prevalence of tumor dissemination.
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Authors
Nicolas Poté, Valérie Paradis,