Intérêt du dosage de la bêta-2-microglobuline dans différents milieux biologiques

Normal values are 1,1 to 2.4 mg/ L in serum, 0.8 to 1.8 mg/L in CSF, <0,37 mg/24 h or <0,28 mg per gram of creatinine in urines. The β2-M is a first-line marker in multiple myeloma and malignant B lymphomas. It is also measured in monitoring of renal function, in some circumstances such as haemodialysis or kidney transplantation, and for the prognosis and therapeutic follow-up of HIV infection and some chronic inflammatory diseases. Other applications of the assay of β2-M as the bone metabolism may expand the scope of interest of this molecule.