| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7665864 | Revue Francophone des Laboratoires | 2006 | 12 Pages |
Abstract
Autoimmunity results from a break down of mechanisms responsible for maintaining tolerance to self-antigens. Multiple factors, innate and acquired, have been implicated. This tolerance breakdown conducts to the selection and to the rescue of autoreactive B and T lymphocytes. Then, high-affinity autoantibodies, immune complexes and autoreactive cytotoxic T lymphocytes may contribute to the clinical symptomatology.
Keywords
autoantibodiesTCR:Virus d'Epstein-BarrCentre germinatifCI:Polyarthrite rhumatoïdehuman leucocyte antigenAuto-anticorpsinterferoninterleukineAutoimmune diseasesMaladies auto-immunesgranulocyte-macrophage colony-stimulating factorFacteurs rhumatoïdesColony-stimulating factortumor necrosis factorLymphocytesRéponse immunitaireImmune responseHeat shock proteinsRecombination activating genesGranulocyteGlobules rougesB cell receptorT cell receptor
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Pierre Youinou, Yves Renaudineau,