Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7669842 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2018 | 7 Pages |
Abstract
We have developed a new turn-on fluorescent probe 1 based on 7-nitro-2,1,3-benzoxadiazole (NBD) with high selectivity and sensitivity for Cys/Hcy on account of nucleophilic substitution and Smiles rearrangement reaction. The probe could sense Cys/Hcy rapidly, the intensity of fluorescence increased immediately within 1Â min. Furthermore, the probe is low toxic and has been successfully applied to detect intracellular Cys/Hcy by cell fluorescence imaging in normal and cancer cells.231
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Authors
Jiamin Wang, Linqiang Niu, Jing Huang, Zhijie Yan, Jianhong Wang,