Article ID Journal Published Year Pages File Type
7669842 Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2018 7 Pages PDF
Abstract
We have developed a new turn-on fluorescent probe 1 based on 7-nitro-2,1,3-benzoxadiazole (NBD) with high selectivity and sensitivity for Cys/Hcy on account of nucleophilic substitution and Smiles rearrangement reaction. The probe could sense Cys/Hcy rapidly, the intensity of fluorescence increased immediately within 1 min. Furthermore, the probe is low toxic and has been successfully applied to detect intracellular Cys/Hcy by cell fluorescence imaging in normal and cancer cells.231
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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