Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7673233 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2013 | 6 Pages |
Abstract
- We studied selected cholinesterase modulators - oximes with calf thymus DNA.
- The binding constants were determinate from titrations (KÂ =Â 3.5Â ÃÂ 104 to 1.4Â ÃÂ 105Â Mâ1).
- Electrophoretic techniques proved that ligand 2 inhibited topoisomerase I (5 μM).
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jana Janockova, Zuzana Gulasova, Kamil Musilek, Kamil Kuca, Maria Kozurkova,