| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7676513 | Talanta | 2018 | 8 Pages |
Abstract
We established a DNase I enzyme-aided fluorescence amplification method for colorectal cancer exosome detection based on graphene oxide (GO)-DNA aptamers interaction, with good sensitivity and simple operation. The limit of detection of this method for colorectal cancer exosome is 2.1â¯Ãâ¯104 particles/μl. This method was also verified in 19 clinical blood serum samples (5â¯Î¼l) to distinguish healthy and colorectal cancer patients, which showed significant diagnostic power.175
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Authors
Hui Wang, Hui Chen, Zhipeng Huang, Tengda Li, Anmei Deng, Jilie Kong,