| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7676871 | Talanta | 2018 | 6 Pages |
Abstract
A robust and ultrasensitive bio-sensor based on the target-aptamer recognition strategy and microscopic enumeration of gold nanoparticles (AuNPs) using dark field microscopy (DFM) was developed. In this assay, upon addition of target molecule, the AuNPs that linearly related to the concentration of target molecules released from the MB were optically counted. The limit of detection was determined to be 2.54â¯fM using thrombin as a model target.144
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Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Rui Yang, Shuwen Liu, Zhenjie Wu, Ying Tan, Shuqing Sun,