Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7681079 | Talanta | 2014 | 5 Pages |
Abstract
Silver nanoparticles (AgNPs) exhibited better chemiluminescence (CL) catalysis activity and smaller nanoparticles have stronger catalysis ability in luminol-K3Fe(CN)6 system among the synthesized AgNPs of different size. 10±2 nm nanoparticles was used as catalysts to enhance the reaction sensitivity. It was found that the CL intensity of AgNPs-luminol-K3Fe(CN)6 was strongly inhibited in the presence of 2-methoxyestradiol (2-ME) and the relative CL intensity was in linear correlation with the concentration of 2-ME. Thus, the silver nanoparticles-enhanced CL method for the determination of 2-ME was developed. The proposed method has a detection limit (3 Sb/K) of 5.0Ã10â10 mol Lâ1 with a relative standard deviation of 0.75% for 5.0Ã10â8 mol Lâ1 2-ME. The method was successfully applied for determination of 2-ME in human serum and pharmaceutical preparations. The possible CL reaction mechanism was also discussed briefly. Oxygen radicals played an important role in the catalytic process.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Min Zhang, Xiangqin Xiao, Wenyuan Zeng, Xiaoying Zeng, Hanchun Yao,