Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7681422 | Talanta | 2013 | 6 Pages |
Abstract
It was found that Hg2+ can inhibit the peroxidase mimetic activity of bovine serum albumin (BSA) protected Au clusters (BSA-Au) due to the specific interaction between Hg2+ and Au+ existed onto the surface of BSA-Au clusters. By coupling with 3, 3â², 5, 5â²-tetramethylbenzidine (TMB)-H2O2 chromogenic reaction, a novel method for Hg2+ detection was developed based on the inhibiting effect of Hg2+ on BSA-Au clusters peroxidase-like activity. This method exhibited high selectivity and sensitivity. As low as 3 nM (0.6 ppb, 3Ï) Hg2+ could be detected with a linear range from 10 nM (2 ppb) to 10 µM (2 ppm) and this method was successfully applied for the determination of total mercury content in skin lightening products.
Related Topics
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Authors
Rui Zhu, Yan Zhou, Xi-Liang Wang, Li-Ping Liang, Yi-Juan Long, Qin-Long Wang, Hai-Jie Zhang, Xiao-Xiao Huang, Hu-Zhi Zheng,