| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7682936 | Talanta | 2013 | 8 Pages |
Abstract
⺠Lectin biosensor based on gold nanoparticles detects glycoproteins down to attomolar (aM) concentration level. ⺠A 2-D array of gold nanoparticles were characterised by AFM, SEM and SPR. ⺠The biosensor performance was validated by fluorescent lectin microarray. ⺠The device was able to quantify glycan amount on a glycoprotein in a quantitative way. ⺠The biosensor has a great potential to be employed in an early biomedical diagnosis of various diseases including cancer.
Keywords
PVAAFM6-mercaptohexanolSambucus nigra agglutininasfFETSAMAuNPsSelf-assembled monolayer (SAM)deionised waterAsialofetuin11-mercaptoundecanoic acidEISSurface plasmon resonanceSPRSelf-assembled monolayerMUASialic acidElectrochemical impedance spectroscopyElectrochemical impedance spectroscopy (EIS)FetuinLectinatomic force microscopyGold nanoparticlesPoly(vinyl alcohol)glycoproteins
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Tomas Bertok, Alena Sediva, Jaroslav Katrlik, Pavol Gemeiner, Milan Mikula, Martin Nosko, Jan Tkac,