| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7684507 | Talanta | 2012 | 10 Pages |
Abstract
⺠Investigation of unknown impurities in capreomycin was carried out. ⺠LC-ion trap MS was used for the characterization. ⺠Fragmentation pattern of the main components is described for the first time. ⺠14 UNK impurities that were never described before, were (partially) characterized.
Keywords
MDR-TBDAPTOFEMAACNuNKARBMSNSHSCIDLC–UVESIViomycinCelCMNIPRnuclear magnetic resonance2,3-diaminopropionic acidLC/MSamino acidEuropean Medicines agencyCollision-induced dissociationVioAcetonitrileFormic acidNMRIon trapTime-of-Flight World Health OrganizationMultidrug Resistant TuberculosisMulti-stage mass spectrometryMass spectrometryreversed phaseImpurity characterizationUnknownHILICarbitrary unitstubCapreomycinhydrophilic interaction chromatographyliquid chromatographyliquid chromatography coupled to mass spectrometryWHOelectrospray ionization
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Shruti Chopra, Murali Pendela, Jos Hoogmartens, Ann Van Schepdael, Erwin Adams,