| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7685455 | Talanta | 2012 | 8 Pages |
Abstract
⺠We monitor the critical quality attributes of a pharmaceutical solid formulation. ⺠Near infrared spectroscopy allows obtaining of both chemical and physical information of the process. ⺠Faster, simpler, accurate and more precise methods are obtained using multivariate calibration models.
Keywords
PLSUS-FDARMSESOPsAPISNVCQANIRSPCAUnited States Food and Drug AdministrationStandard normal variateISOPrincipal component analysisProcess analytical technologyPartial least squaresStandard operating proceduresPartial least-squares regressionRoot mean square errorInternational Organization for StandardizationNear-infrared spectroscopyActive Pharmaceutical IngredientNear Infrared spectroscopyCritical quality attributepathigh-performance liquid chromatographyHPLC
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Juan G. Rosas, Marcel Blanco, Josep M. González, Manel Alcalà ,