| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7685889 | Talanta | 2012 | 12 Pages |
Abstract
⺠Heart-shaped tablets were coated with a thin HPMC film up to approx. 28 μm on the tablet face. ⺠In different PCA models the dominating factors and their spectral effects of each coating step could be identified. ⺠The distinct separation of HPMC coating growth and tablet moisture in different PCs was elaborated. ⺠PLS models were developed for the determination of tablet moisture, tablet weight gain and coating growth. ⺠At-line NIR Chemical Imaging in combination with PLSDA verified the coating growth information.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
C.-V. Möltgen, T. Puchert, J.C. Menezes, D. Lochmann, G. Reich,