Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7687082 | Talanta | 2012 | 10 Pages |
Abstract
⺠Gel-based bottom-up MS approach for characterizing Pt-protein complexes. ⺠nrSDS-PAGE separation and conventional in gel digestion preserve Pt-protein bonds. ⺠Sulfur-containing reagents have a negative impact on Pt-protein bonds preservation. ⺠Cisplatin binding sites (Met, His, Cys) identified in HSA, TF, CA, MYO and CYT C.
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Authors
EstefanÃa Moreno-Gordaliza, Benito Cañas, MarÃa A. Palacios, M. Milagros Gómez-Gómez,