Article ID Journal Published Year Pages File Type
7687170 Talanta 2011 8 Pages PDF
Abstract
► A label-free fluorescence detection method for DNA is designed using functional magnetic nanoparticles (MNPs) as trapping and detection probes. ► Microwave heating is employed to assist in the fabrication of detection probes and to accelerate the detection processes for the target DNA. The full period for analysis is only about 1 h. ► The detection limit is as low as 40 pM. Furthermore, examining the sensing results through the naked eye is possible when the DNA concentration in the sample is ≥10 nM. ► This approach is potentially suitable for the rapid sensing of target DNAs from sample solutions in terms of qualitative and semi-quantitative high throughput analysis.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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