Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7687170 | Talanta | 2011 | 8 Pages |
Abstract
⺠A label-free fluorescence detection method for DNA is designed using functional magnetic nanoparticles (MNPs) as trapping and detection probes. ⺠Microwave heating is employed to assist in the fabrication of detection probes and to accelerate the detection processes for the target DNA. The full period for analysis is only about 1 h. ⺠The detection limit is as low as 40 pM. Furthermore, examining the sensing results through the naked eye is possible when the DNA concentration in the sample is â¥10 nM. ⺠This approach is potentially suitable for the rapid sensing of target DNAs from sample solutions in terms of qualitative and semi-quantitative high throughput analysis.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Ju-Yu Lin, Yu-Chie Chen,