Article ID Journal Published Year Pages File Type
7687867 TrAC Trends in Analytical Chemistry 2018 68 Pages PDF
Abstract
For controlled release drug delivery applications, numerous PLGA based micro and nanospheres have been extensively studied. In order to describe the mechanisms involved during PLGA degradation, erosion and drug release from the bulk polymer, various mathematical models have been proposed. Along with describing the current state of art of mathematical modeling in drug dissolution, the review article addresses the role of autocatalysis in mass transport and chemical reaction phenomenon of drug delivery from polymeric drug delivery systems.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
, ,