Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7689745 | TrAC Trends in Analytical Chemistry | 2014 | 18 Pages |
Abstract
- Ultra-high-performance liquid chromatography UHPLC is the standard LC platform.
- Columns packed with sub-2µm particles come for chiral-LC, SEC, IEX, HILIC and SFC.
- Detailed characterization of biopharmaceuticals is an important UHPLC application.
- Particle-size reduction and system-pressure increase are technologically difficult.
- Superficially porous particles directly improve the kinetic performance of UHPLC.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Szabolcs Fekete, Julie Schappler, Jean-Luc Veuthey, Davy Guillarme,