Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations

Article ID	Journal	Published Year	Pages	File Type
7692565	Chemistry and Physics of Lipids	2012	18 Pages	PDF

Abstract

âº Mapping of lipids by MALDI-MSI. âº Biochemical microscopy of DHA-containing lipids. âº MALDI-MSI of lipid oxidation products in acute lung injury. âº MALDI-MSI detection of lipid response to traumatic brain injury. âº MALDI-MSI detection of cardiolipin.

Keywords

4-HHE TFA DHB Q-TOF HBSS CCI PLC MSN TIC MSI ISD TOF 9-AA Phospholipase-C DESI TBI FT-ICR NIMS TOCl TLCL total ion count IMS ESI PND PBS 4-HNE 4-hydroxynonenal 2,5-dihydroxybenzoic acid 4-Hydroxyhexenal 9-Aminoacridine H&E MS/MS Traumatic brain injury Acute lung injury sphingomyelin Trifluoroacetic acid docosahexaenoic acid phosphatidic acid PUFA Ali Indium tin oxide ITO cornu ammonis mass spectrometry imaging MALDI imaging matrix-assisted laser desorption/ionization CNS DHA diacylglycerol Fourier transform ion cyclotron resonance DAG postnatal day Time-of-Flight quadrupole time-of-flight Cer ceramide Sulfatide central nervous system SIMS secondary ion mass spectrometry Mass spectrometry Tandem mass spectrometry Ion mobility spectrometry In-source decay phosphatidylinositol phosphatidylcholine phosphatidylglycerol phosphatidylethanolamine Phosphatidylserine Phospholipid Lipidomics MALDI Phosphate-buffered saline Hank's balanced salt solution NAO Hematoxylin and Eosin Lipid peroxidation Cardiolipin liquid chromatography controlled cortical impact electrospray ionization desorption electrospray ionization