Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7692764 | Chemistry and Physics of Lipids | 2012 | 8 Pages |
Abstract
⺠We report novel diacylacetate quaternized amine (AQ) zwitterionic lipids. ⺠AQ lipids exhibit transition temperatures similar to those of PE lipids. ⺠AQ lipids interact with anions according to the Hofmeister series. ⺠AQ liposomes demonstrate similar in vivo properties to DSPC liposomes. ⺠AQ lipids have distinct biophysical properties from PC lipids that may be useful in drug delivery.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Aditya G. Kohli, Colin L. Walsh, Francis C. Szoka,