Article ID Journal Published Year Pages File Type
7693838 Current Opinion in Chemical Biology 2018 10 Pages PDF
Abstract
Great progress has been made in expanding the repertoire of genetically encoded fluorescent sensors for monitoring intracellular transition metals (TMs). This powerful toolkit permits dynamic and non-invasive detection of TMs with high spatial-temporal resolution, which enables us to better understand the roles of TM homeostasis in both physiological and pathological settings. Here we summarize the recent development of genetically encoded fluorescent sensors for intracellular detection of TMs such as zinc and copper, as well as heavy metals including lead, cadmium, mercury, and arsenic.
Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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