Article ID Journal Published Year Pages File Type
7694192 Current Opinion in Chemical Biology 2016 10 Pages PDF
Abstract

- To date, all tetracycline antibiotics are fermentation products or are derived from them.
- A fully synthetic route provides access to tetracyclines of unprecedented structural variability.
- Eravacycline and two other clinical candidates are discovered by platform synthetic technology.
- Practical manufacture of eravacycline is enabled by a fully synthetic route.
Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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