Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7694192 | Current Opinion in Chemical Biology | 2016 | 10 Pages |
Abstract
- To date, all tetracycline antibiotics are fermentation products or are derived from them.
- A fully synthetic route provides access to tetracyclines of unprecedented structural variability.
- Eravacycline and two other clinical candidates are discovered by platform synthetic technology.
- Practical manufacture of eravacycline is enabled by a fully synthetic route.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Fan Liu, Andrew G Myers,