Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7694445 | Current Opinion in Chemical Biology | 2015 | 8 Pages |
Abstract
- γ-Butyrolactone (GBL) hormones regulate antibiotic production in many Streptomyces species.
- GBL-based systems could be used to design orthogonal switches in synthetic biology.
- The GBL receptor ScbR has been used in mammalian synthetic switches.
- The chemical diversity of GBLs could be used for multi-input/multi-channel devices.
- Understanding natural GBL circuit complexity will guide the design of new systems.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Marc Biarnes-Carrera, Rainer Breitling, Eriko Takano,