Article ID Journal Published Year Pages File Type
7694445 Current Opinion in Chemical Biology 2015 8 Pages PDF
Abstract

- γ-Butyrolactone (GBL) hormones regulate antibiotic production in many Streptomyces species.
- GBL-based systems could be used to design orthogonal switches in synthetic biology.
- The GBL receptor ScbR has been used in mammalian synthetic switches.
- The chemical diversity of GBLs could be used for multi-input/multi-channel devices.
- Understanding natural GBL circuit complexity will guide the design of new systems.
Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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