| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7694501 | Current Opinion in Chemical Biology | 2015 | 8 Pages |
Abstract
- Combining unnatural mutagenesis with ligation allows sidechain and backbone labeling.
- Two unnatural amino acids are incorporated using two stop codons or four base codons.
- Mutually orthogonal reactions with unnatural amino acids used for double labeling.
- Libraries of doubly labeled proteins could be used for determining dynamic structures.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Conor M Haney, Rebecca F Wissner, E James Petersson,