Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7694658 | Current Opinion in Chemical Biology | 2015 | 9 Pages |
Abstract
- Next-generation sequencing of peripheral B cells (BCR-seq) in health and disease states.
- Serum antibody proteomics (Ig-seq) complements BCR-seq in analyzing endpoint functionality.
- Advances in the pairing and NGS of antibody heavy chain and light chain (VH:VL) sequences.
- Combined, BCR-seq and Ig-seq provide a clear advance in antibody discovery.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Jason J Lavinder, Andrew P Horton, George Georgiou, Gregory C Ippolito,