| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7694984 | Current Opinion in Chemical Biology | 2012 | 9 Pages |
Abstract
⺠New 3D structural insights have revealed the action of key mammalian O-glycosyltransferases and N-glycosyltransferases. ⺠N-glycosylation may involve amide 'twisiting' to active the nucleophile. ⺠New compounds harness unusual mechanisms to inhibit O-GlcNAc transferases. ⺠Protein fucosylation unveiled in PoFUT1 and PoFUT2. ⺠SNi mechanisms are placed on a firmer experimental foundation.
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Authors
Ramon Hurtado-Guerrero, Gideon J Davies,