| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7694991 | Current Opinion in Chemical Biology | 2012 | 10 Pages |
Abstract
⺠O-GlcNAc levels in cells respond to availability of nutrients including glucose. ⺠OGT and OGA are the two enzymes processing hundreds of O-GlcNAc modified proteins. ⺠Catalysis by OGA and OGT is being studied using kinetic and structural approaches. ⺠OGA processes metabolic derivatives of O-GlcNAc from proteins. ⺠The substrate specificity and regulation of OGA and OGT merit further attention.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
David J Vocadlo,