Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7695055 | Current Opinion in Chemical Biology | 2012 | 8 Pages |
Abstract
⺠We developed azaelectrocyclization-based labeling of proteins and peptides. ⺠PET-imaging of glycoproteins visualized the circulatory residence of the proteins. ⺠PET and fluorescence imaging of N-glycan dendrimers revealed their dynamics. ⺠The imaging of the fluorescence-labeled lymphocytes visualized the trafficking. ⺠The lymphocytes engineered by an N-glycan targeted the DLD-1 human colon carcinoma.
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Authors
Koichi Fukase, Katsunori Tanaka,