| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7751960 | Inorganica Chimica Acta | 2012 | 19 Pages |
Abstract
⺠Rhodium(III) and iridium(III) complexes with polypyridyl ligands are effective cytotoxic agents. ⺠Selectivity for malignant cells can be improved by employing substituted phenanthroline ligands. ⺠Cellular impact of half-sandwich complexes depends on the donor properties of their facial coligands. ⺠Apoptosis induction and associated high levels of reactive oxygen species. ⺠Dose-dependent inhibition of mitochondrial respiration.
Related Topics
Physical Sciences and Engineering
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Authors
Yvonne Geldmacher, Melanie Oleszak, William S. Sheldrick,