Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7753001 | Journal of Fluorine Chemistry | 2015 | 8 Pages |
Abstract
- A synthesis of difluorinated α-C-galactosylceramides analogs is reported.
- The CF2-glycoside core is prepared from galactal using a domestic methodology.
- The phytosphingosine side-chain is settled via an original O-2 to C-1â² transfer.
- The resulting analogs were not active for iNKT cell activation.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Sophie Colombel, Nathalie Van Hijfte, Thomas Poisson, Xavier Pannecoucke, Fanny Monneaux, Eric Leclerc,