| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7753300 | Journal of Fluorine Chemistry | 2014 | 13 Pages |
Abstract
A one-pot gold(I)-catalysed regioselective method for the preparation of 3-fluoro-tetrahydropyran-4-one derivatives from homopropargyl acetal is described. The transformation is based on a Petasis-Ferrier rearrangement and a subsequent electrophilic fluorination. The 3-fluoro-pyran-4-one product acts as a protected precursor of alkylfluoro-α,β-(E)-unsaturated ketone.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Jon Erik Aaseng, Naseem Iqbal, Christian A. Sperger, Anne Fiksdahl,