Article ID Journal Published Year Pages File Type
7753538 Journal of Fluorine Chemistry 2013 7 Pages PDF
Abstract
► Three bioisosteric fragments with deshielded fluorines have been compared and analyzed in the interactions with α helices. ► The rule of shielding has been applied to the design of novel peptidomimetics containing shielded fluorine atoms. ► The phi-psi conformational space of these fluorinated peptidomimetics has been analyzed and compared to other peptides.
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
Authors
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