Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7753538 | Journal of Fluorine Chemistry | 2013 | 7 Pages |
Abstract
⺠Three bioisosteric fragments with deshielded fluorines have been compared and analyzed in the interactions with α helices. ⺠The rule of shielding has been applied to the design of novel peptidomimetics containing shielded fluorine atoms. ⺠The phi-psi conformational space of these fluorinated peptidomimetics has been analyzed and compared to other peptides.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Claudio Dalvit, Soo Young Ko, Anna Vulpetti,