Article ID Journal Published Year Pages File Type
7753572 Journal of Inorganic Biochemistry 2018 23 Pages PDF
Abstract
Murine macrophages were treated with [Fe(NO)2]-modified low-density lipoprotein. The resulting increase of total cellular iron level was not accompanied with inducible nitric oxide synthase gene induction. In vitro plasmid nicking assay indicated that chelation of iron in the form of DNIC reduced the iron-related, reactive oxygen species-mediated DNA damage.107
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
Authors
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