Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7753572 | Journal of Inorganic Biochemistry | 2018 | 23 Pages |
Abstract
Murine macrophages were treated with [Fe(NO)2]-modified low-density lipoprotein. The resulting increase of total cellular iron level was not accompanied with inducible nitric oxide synthase gene induction. In vitro plasmid nicking assay indicated that chelation of iron in the form of DNIC reduced the iron-related, reactive oxygen species-mediated DNA damage.107
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Hanna Lewandowska, Tomasz M. StÄpkowski, Sylwia MÄczyÅska-Wielgosz, Katarzyna Sikorska, JarosÅaw SadÅo, Jakub Dudek, Marcin Kruszewski,