| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7753596 | Journal of Inorganic Biochemistry | 2018 | 12 Pages |
Abstract
Ferrocenyl compounds with tropolone co-ligands showed improved activities on Trypanosoma brucei and selectivities towards the pathogen in respect to the ligands. Compounds were active on Leishmania infantum and Mycobacterium tuberculosis but poorly selective. Interference with the thiol-redox homeostasis of T. brucei was not detected but DNA could be a target.98
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Feriannys Rivas, Andrea Medeiros, Esteban RodrÃguez Arce, Marcelo Comini, Camila M. Ribeiro, Fernando R. Pavan, Dinorah Gambino,