| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7753602 | Journal of Inorganic Biochemistry | 2018 | 12 Pages |
Abstract
Three copper(II) compounds containing sulfonamides and (N^N)-bidentate ligands were prepared and showed nuclease properties, cleaving plasmid DNA at low micromolar concentration. Both sulfonamide and (N^N)-ligand modulate the magnitude and preferred mode of interaction with DNA. The nuclease activity of the compounds correlates with their promising antimycobacterial and antiproliferative activities.75
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Douglas H. Nakahata, Raphael E.F. de Paiva, Wilton R. Lustri, Camila M. Ribeiro, Fernando R. Pavan, Gisele G. da Silva, Ana L.T.G. Ruiz, João E. de Carvalho, Pedro P. Corbi,