Article ID Journal Published Year Pages File Type
7753637 Journal of Inorganic Biochemistry 2018 9 Pages PDF
Abstract
Ga(III) complexes of thiosemicarbazones significantly depleted cellular iron, resulting in upregulation of transferrin receptor-1 and downregulation of ferritin. They also effectively activate the caspase family proteins (caspase-3/7/9), promote the release of cytochromes from the mitochondria, and ultimately lead to apoptosis.151
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
Authors
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