| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7753663 | Journal of Inorganic Biochemistry | 2018 | 30 Pages |
Abstract
A novel hydrosoluble complex of AuI with tris-(2-carboxyethyl)phosphine (TCEP) is reported. Antiproliferative assays against nine tumorigenic and one non-tumorigenic cell lines demonstrate selectivity against ovarian cancer. Investigation on the substitution reactions toward sulfur-rich proteins reveals the complex is inert to such reactions suggesting less toxic effects.187
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
S.Q. Gomes, L. Vitoriano, E.G.R. de Arruda, A.L.T.G. Ruiz, T. Candido, J.E. de Carvalho, W.R. Lustri, C. Abbehausen,