| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7753694 | Journal of Inorganic Biochemistry | 2018 | 35 Pages |
Abstract
99mTc(I) and Re (I) complexes with sulfonamide or sulfocoumarin targeting units were synthesized as potential hypoxia tumor imaging agents. The Re sulfocoumarin derivatives were inactive against hCA-I, -II and -IV, but exhibited moderate affinity for hCA-IX. However, uptake in HT-29 tumors was highest for the 99mTc sulfoamide derivative.193
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Inorganic Chemistry
Authors
Misaki Nakai, Jihne Pan, Kuo-Shyan Lin, John R. Thompson, Alessio Nocentini, Claudiu T. Supuran, Yasuo Nakabayashi, Tim Storr,