| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7753705 | Journal of Inorganic Biochemistry | 2018 | 38 Pages |
Abstract
Cytochromes P450 and H2O2 have a complex relationship that involves three aspects: (1) H2O2 production through an uncoupling mechanism. (2) Peroxidase/peroxygenase reactions that use H2O2 as an oxygen donating co-substrate. (3) H2O2-dependent inhibition of P450 through oxidation of the heme-thiolate ligand.169
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Matthew E. Albertolle, F. Peter Guengerich,