| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7753774 | Journal of Inorganic Biochemistry | 2018 | 14 Pages |
Abstract
We assessed the transglutaminase-mediated conjugation and the labelling with nitride-technetium-99m on a bis(thiosemicarbazone) chelator. Diacetyl-2-(N4-methyl-3-thiosemicarbazone)-3-(N4-amino-3-thiosemicarbazone) was modified with 6-aminohexanoic acid and conjugated with Substance P via transglutaminase. The products were labelled with nitride technetium(V)-99g/99m and the complexes were characterized, compared with the 64Cu-analogues and their in vitro stability was tested.55
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Physical Sciences and Engineering
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Inorganic Chemistry
Authors
Nicola Salvarese, Barbara Spolaore, Selena Marangoni, Anna Pasin, Alessandro Galenda, Sergio Tamburini, Gianfranco Cicoria, Fiorenzo Refosco, Cristina Bolzati,