| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7753844 | Journal of Inorganic Biochemistry | 2018 | 25 Pages |
Abstract
The thermodynamic activity-based Michaelis constants Kma of poorly water-soluble substrates are calculated from the experimentally determined concentration-based Michaelis constants Kmc and the activity coefficient at infinite dilution γâ. The evaluation of γâ in complex solvent mixtures by molecular dynamics simulations provides a predictive tool for the design of biocatalytic processes.79
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Valerio Ferrario, Niels Hansen, Jürgen Pleiss,