Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7753901 | Journal of Inorganic Biochemistry | 2018 | 22 Pages |
Abstract
The tetranuclear cytotoxic Pt complex reactivity study toward model proteins allows initial identification of lysozyme adducts formation and characterization by mass spectrometry and crystallographic determination. Selected features of the interactions observed were reproduced by reacting the Pt complex with N-methylimidazole. One possible pathway indicates its activation through cluster disassembly.125
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Tiziano Marzo, Francisco Navas, Damiano Cirri, Antonello Merlino, Giarita Ferraro, Luigi Messori, Adoracion G. Quiroga,